• The results serve to disprove the tetranucleotide hypothesis. It is, however, noteworthy-whether this is more than accidental, cannot yet be said-that in all desoxypentose nucleic acids examined thus far the molar ratios of total purines to total pyrimidines, and also of adenine to thymine and of guanine to cytosine, were not far from 1.

    Erwin Chargaff (1978). “Heraclitean Fire: Sketches from a Life Before Nature”, p.93, Paul & Company Pub Consortium