Authors:
  • To demonstrate experimentally that a microscopic organism actually is the cause of a disease and the agent of contagion, I know no other way, in the present state of Science, than to subject the microbe (the new and happy term introduced by M. Sédillot) to the method of cultivation out of the body.

    Hippocrates, Ambroise Paré, William Harvey, Edward Jenner, Oliver Wendell Holmes (1910). “Scientific Papers; Physiology, Medicine, Surgery, Geology”