The true worth of an experimenter consists in his pursuing not only what he seeks in his experiment, but also what he did not seek.
Particular facts are never scientific; only generalization can establish science.
Science increases our power in proportion as it lowers our pride.
Our ideas are only intellectual instruments which we use to break into phenomena; we must change them when they have served their purpose, as we change a blunt lancet that we have used long enough.
A great discovery is a fact whose appearance in science gives rise to shining ideas, whose light dispels many obscurities and shows us new paths.
When entering on new ground we must not be afraid to express even risky ideas so as to stimulate research in all directions. As Priestley put it, we must not remain inactive through false modesty based on fear of being mistaken.
The joy of discovery is certainly the liveliest that the mind of man can ever feel.
A discovery is generally an unforeseen relation not included in theory.
I do not ... reject the use of statistics in medicine, but I condemn not trying to get beyond them and believing in statistics as the foundation of medical science. ... Statistics ... apply only to cases in which the cause of the facts observed is still [uncertain or] indeterminate. ... There will always be some indeterminism ... in all the sciences, and more in medicine than in any other. But man's intellectual conquest consists in lessening and driving back indeterminism in proportion as he gains ground for determinism by the help of the experimental method.
The doubter is a true man of science: he doubts only himself and his interpretations, but he believes in science.
Experiment is fundamentally only induced observation.
The science of life is a superb and dazzlingly lighted hall which may be reached only by passing through a long and ghastly kitchen.
First causes are outside the realm of science.
The eloquence of a scientist is clarity; scientific truth is always more luminous when its beauty is unadorned than when it is tricked out in the embellishments with which our imagination would seek to clothe it.
In science, the best precept is to alter and exchange our ideas as fast as science moves ahead.
To be worthy of the name, an experimenter must be at once theorist and practitioner. While he must completely master the art of establishing experimental facts, which are the materials of science, he must also clearly understand the scientific principles which guide his reasoning through the varied experimental study of natural phenomena. We cannot separate these two things: head and hand. An able hand, without a head to direct it, is a blind tool; the head is powerless without its executive hand.
We must never make experiments to confirm our ideas, but simply to control them.
The better educated we are and the more acquired information we have, the better prepared shall we find our minds for making great and fruitful discoveries.
Ardent desire for knowledge, in fact, is the one motive attracting and supporting investigators in their efforts; and just this knowledge, really grasped and yet always flying before them, becomes at once their sole torment and their sole happiness. Those who do not know the torment of the unknown cannot have the joy of discovery which is certainly the liveliest that the mind of man can ever feel.
The investigator should have a robust faith - and yet not believe.
Hatred is the most clear- sighted, next to genius.
The stability of the internal medium is a primary condition for the freedom and independence of certain living bodies in relation to the environment surrounding them.
The physiologist is not a man of the world, he is a scientist, a man caught and absorbed by a scientific idea that he pursues; he no longer hears the cries of the animals, no longer sees the flowing blood, he sees only his idea: organisms that hide from him problems that he wants to discover. He doesn't feel that he is in a horrible carnage; under the influence of a scientific idea, he pursues with delight a nervous filament inside stinking and livid flesh that for any other person would be an object of disgust and horror.
[Those] who have an excessive faith in their theories or in their ideas are not only poorly disposed to make discoveries, but they also make very poor observations.
If I had to define life in a single phrase, I should clearly express my thought of throwing into relief one characteristic which, in my opinion, sharply differentiates biological science. I should say: life is creation.
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