Thanks to our present surgical methods in physiology we can demonstrate at any time almost all phenomena of digestion without the loss of even a single drop of blood, without a single scream from the animal undergoing the experiment.
Our success was mainly due to the fact that we stimulated the nerves of animals that easily stood on their own feet and were not subjected to any painful stimulus either during or immediately before stimulation of their nerves.
The digestive canal represents a tube passing through the entire organism and communicating with the external world, i.e. as it were the external surface of the body, but turned inwards and thus hidden in the organism.
Physiology has, at last, gained control over the nerves which stimulate the gastric glands and the pancreas.
The Sun-Paul must consider only one thing: what is the relation of this or that external reaction of the animal to the phenomena of the external world?
As we have seen, bread, and especially dry bread, evokes secretion of considerably larger quantities of saliva than meat.
As was to be expected, the discovery of the nervous apparatus of the salivary glands immediately impelled physiologists to seek a similar apparatus in other glands lying deeper in the digestive canal.
It has long been known for sure that the sight of tasty food makes a hungry man's mouth water; also lack of appetite has always been regarded as an undesirable phenomenon, from which one might conclude that appetite is essentially linked with the process of digestion.
Edible substances evoke the secretion of thick, concentrated saliva. Why? The answer, obviously, is that this enables the mass of food to pass smoothly through the tube leading from the mouth into the stomach.
One can truly say that the irresistible progress of natural science since the time of Galileo has made its first halt before the study of the higher parts of the brain, the organ of the most complicated relations of the animal to the external world. And it seems, and not without reason, that now is the really critical moment for natural science; for the brain, in its highest complexity-the human brain-which created and creates natural science, itself becomes the object of this science.
The gastric laboratory uses its protein ferment under an acid reaction.
The physiologist who succeeds in penetrating deeper and deeper into the digestive canal becomes convinced that it consists of a number of chemical laboratories equipped with various mechanical devices.
Finally, as the digestive canal is a complex system, a series of separate chemical laboratories, I cut the connections between them in order to investigate the course of phenomena in each particular laboratory; thus I resolved the digestive canal into several separate parts.
The digestive canal is in its task a complete chemical factory. The raw material passes through a long series of institutions in which it is subjected to certain mechanical and, mainly, chemical processing, and then, through innumerable side-streets, it is brought into the depot of the body. Aside from this basic series of institutions, along which the raw material moves, there is a series of lateral chemical manufactories, which prepare certain reagents for the appropriate processing of the raw material.
In the case of the stomach, however, the nerves of the glandular cells were always severed when constructing an artificially isolated pouch and this, naturally, affected the normal work of the stomach.
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