We find in the history of ideas mutations which do not seem to correspond to any obvious need, and at first sight appear as mere playful whimsies such as Apollonius' work on conic sections, or the non-Euclidean geometries, whose practical value became apparent only later.
If life really depends on each gene being as unique as it appears to be, then it is too unique to come into being by chance mutations.
We are embedded in the great evolutionary story of planet Earth, the spare, elegant process of mutation and selection and bricolage. And this means that we are anything but alone.
Programmed by quanta, physics gave rise first to chemistry and then to life; programmed by mutations and recombination, life gave rise to Shakespeare; programmed by experience and imagination, Shakespeare gave rise to Hamlet.
Many words are in a state of mutation, the pronunciation being unsettled even in the best society, a result that must often arise where language is as variable and undetermined as the English.
In my practice, the majority of mutation carriers choose mastectomy; however, for those without cancer, they have much more control over the timing. For younger women, we might wait until they have found a life partner, or until after childbearing. Older women who find out they carry a mutation have unwittingly escaped a large percentage of their risk, and therefore, the calculated future risk is not necessarily a daunting number.
As a gender variant visual artist I access 'technologies of gender' in order to amplify rather than erase the hermaphroditic traces of my body. I name myself. A gender abolitionist. A part time gender terrorist. An intentional mutation and intersex by design, (as opposed to diagnosis), in order to distinguish my journey from the thousands of intersex individuals who have had their 'ambiguous' bodies mutilated and disfigured in a misguided attempt at 'normalization'. I believe in crossing the line as many times as it takes to build a bridge we can all walk across.
You're only delaying the inevitable. I have the Tacitus. I am invincible. The Tacitus told me of Tiberium missiles, of invulnerable flying ships, of real-time genetic mutation. More than alien. More than human! The next step in our evolution as a species!
Every batch of sperm represents an opportunity for genetic typos - called de novo mutations - to be passed on. A 20-year-old man and woman will each pass on about 20 de novo mutations to a baby they conceive. By the time the couple is 40, a woman's total has remained at 20, while a man's has jumped to 65 - and it keeps climbing from there.
Cancer can no longer be classified according to the organ in which it arises. It has to be characterized in terms of the genetic mutation that exists.
I was taught over and over again that the accumulation of random mutations led to evolutionary change - led to new species. I believed it until I looked for evidence.
In the early '90s, we discovered mutations that could double the normal life span of worms.
I know that the human condition will be radically changed through technical means. Much of this change will be painful, monstrous and horrible. Most mutations are disgusting failures, most experiments are failures. I accept this and I don't find it frightening.
The differences you perceive between Humans-between groups of Humans-are the result of isolation and inbreeding, mutation, and adaptation to different Earth environments
The art of living has no history: it does not evolve: the pleasure which vanishes vanishes for good, there is no substitute for it. Other pleasures come, which replace nothing. No progress in pleasures, nothing but mutations.
We add that it would be all too easy to object that mutations have no evolutionary effect because they are eliminated by natural selection. Lethal mutations (the worst kind) are effectively eliminated, but others persist as alleles. ...Mutants are present within every population, from bacteria to man. There can be no doubt about it. But for the evolutionist, the essential lies elsewhere: in the fact that mutations do not coincide with evolution.
Mankind will someday realize that we are actually in contact with the dead and with the other world, whatever it is; right now we could predict, if we only exerted enough mental will, what is going to happen within the next hundred years and be able to take steps to avoid all kinds of catastrophes. When a man dies he undergoes a mutation in his brain that we know nothing about now but which will be very clear someday if scientists get on the ball. The bastards right now are only interested in seeing if they can blow up the world.
It is absolutely a good thing that she [Angelina Jolie] helped to educate the world about the existence of this mutation; hopefully, as a result, more compassionate understanding exists regarding the choices BRCA carriers must face.
The Angelina Effect refers to the fact that a powerful, beautiful, well-respected and world-renowned woman unabashedly revealed private medical details about a gene mutation which affects 1 in 500 people. In so doing, she raised awareness and sparked conversations around the world amongst known BRCA carriers, possible carriers, and the circle of family and friends who care about them.
Nearly every BRCA mutation carrier's main concern is how to avoid the fate of relatives who have had, and possibly died from, breast or ovarian cancer.
The food you eat is among the most significant factors affecting your genes and pushing them toward cancer by causing mutation or disruption in their function. That is, what you eat can either prevent cancer and other chronic illnesses or help cause them.
In Darwin's theory, you just have to substitute 'mutations' for his 'slight accidental variations' (just as quantum theory substitutes 'quantum jump' for 'continuous transfer of energy'). In all other respects little change was necessary in Darwin's theory...
... we find ourselves facing a rising tide of biologically active, synthetic organic chemicals. Some tinker with our hormones. Some attach themselves to our chromosomes and trigger mutations. Some cripple the immune system. Some light up our genes and so enhance the production of certain enzymes. If we could metabolize these chemicals into completely benign breakdown products and excrete them, they would pose less of a hazard. Instead, a good many of them accumulate.
Although random mutations influenced the course of evolution, their influence was mainly by loss, alteration, and refinement... Never, however, did that one mutation make a wing, a fruit, a woody stem, or a claw appear. Mutations, in summary, tend to induce sickness, death, or deficiencies. No evidence in the vast literature of heredity changes shows unambiguous evidence that random mutation itself, even with geographical isolation of populations, leads to speciation.
Engaging it produces an intense force, which in turn produces a mutation in consciousness. You become who you really are.
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