Nearly every BRCA mutation carrier's main concern is how to avoid the fate of relatives who have had, and possibly died from, breast or ovarian cancer.
The Angelina Effect refers to the fact that a powerful, beautiful, well-respected and world-renowned woman unabashedly revealed private medical details about a gene mutation which affects 1 in 500 people. In so doing, she raised awareness and sparked conversations around the world amongst known BRCA carriers, possible carriers, and the circle of family and friends who care about them.
It is absolutely a good thing that she [Angelina Jolie] helped to educate the world about the existence of this mutation; hopefully, as a result, more compassionate understanding exists regarding the choices BRCA carriers must face.
In my practice, the majority of mutation carriers choose mastectomy; however, for those without cancer, they have much more control over the timing. For younger women, we might wait until they have found a life partner, or until after childbearing. Older women who find out they carry a mutation have unwittingly escaped a large percentage of their risk, and therefore, the calculated future risk is not necessarily a daunting number.
Cancer can no longer be classified according to the organ in which it arises. It has to be characterized in terms of the genetic mutation that exists.
Occasionally, a great band would come along, like Blondie or OutKast who could be pop and bring interesting ideas into the mainstream at the same time. That's now gone, because of this weird mutation of pop, rap, R&B, bad rave, and supposedly soulful singing on top of it.
Audio virology is not a metaphor. It is to be taken literally. It maps real processes of mutation, transmission, contagion and memory within music culture.
When you get sick with the flu you get infected with flu viruses and they make lots of new flu viruses, but those new viruses are not exact copies of the old ones. They have mutations in them. A lot of those mutations are harmful.
There is some research that suggests that viruses like the flu are really actually kind of at the razor's edge when it comes to mutation. They're mutating so fast that if they mutated much faster they would actually develop a lot of harmful mutations that could slow them down and cripple them and eventually literally drive them extinct.
If you ever meet a guy and you fall in love with him, but because of some weird genetic mutation he doesn't seem to return the feeling?... Wear that dress.
Science fiction [is] the kind of writing that prepares us for the necessary mutations brought about in society from an ever changing technological world and as a result. The mainstream hasn’t excluded SF; the mainstream has excluded itself. No one told Jules Verne he was a science fiction writer, but he invented the 20th century.
Yoga is existential, experiential, experimental. No belief is required, no faith is needed - only courage to experience. And that's what's lacking. You can believe easily because in belief you are not going to be transformed. Belief is something added to you, something superficial. Your being is not changed; you are not passing through some mutation.
It's impossible by micro-mutation to form any new species.
It takes a huge effort to free yourself from memory, but when you succeed, you start to realize that you’re capable of far more than you imagined. You live in this vast body called the Universe, which contains all the solutions and all the problems. Visit your soul; don’t visit your past. The Universe goes through many mutations and carries the past with it. We call each of those mutations a ‘life,’ but just as the cells in your body change and yet you remain the same, so time does not pass, it merely changes.
Religion, a mediaeval form of unreason, when combined with modern weaponry becomes a real threat to our freedoms. This religious totalitarianism has caused a deadly mutation in the heart of Islam and we see the tragic consequences in Paris today.
Cancer is really a slew of rare diseases. Lung cancer has 700 sub-types, breast cancer has 30,000 mutations which means that every cancer in its own right is a rare disease. Sharing data globally in this context is really important from a life-threatening perspective.
The tragedy of a species becoming unfit for life by over-evolving one ability is not confined to humankind. Thus it is thought, for instance, that certain deer in paleontological times succumbed as they acquired overly-heavy horns. The mutations must be considered blind, they work, are thrown forth, without any contact of interest with their environment. In depressive states, the mind may be seen in the image of such an antler, in all its fantastic splendour pinning its bearer to the ground.
New Orleans is a glorious mutation
The messages that DNA molecules contain are all but eternal when seen against the time scale of individual lifetimes. The lifetimes of DNA messages give or take a few mutations are measured in units ranging from millions of years to hundreds of millions of years; or, in other words, ranging from 10,000 individual lifetimes to a trillion individual lifetimes. Each individual organism should be seen as a temporary vehicle, in which DNA messages spend a tiny fraction of their geological lifetimes.
Fundamentalism in most of its forms is the active creation of antibodies to some threatening [god] virus. As long as threatening religions or mutations [heresies] are present, fundamentalism will churn out antibodies to keep the population under control and prevent mutations from getting out of hand.
Faced with a new mutation in an organism, or a fundamental change in its living conditions, the biologist is frequently in no position whatever to predict its future prospects. He has to wait and see. For instance, the hairy mammoth seems to have been an admirable animal, intelligent and well-accoutered. Now that it is extinct, we try to understand why it failed. I doubt that any biologist thinks he could have predicted that failure. Fitness and survival are by nature estimates of past performance.
I have that gene mutation too and it’s not something I would believe in for myself. I wouldn’t call it the brave choice. I actually think it’s the most fearful choice you can make when confronting anything with cancer. My belief is that cancer comes from inside you and so much of it has to do with the environment of your body. It’s the stress that will turn that gene on or not.
The unique nature about the influenza virus is its great potential for changes, for mutation.
Exploitation, mutilation, mutations, confirmation to the evils of the world.
Without equity, pandemic battles will fail. Viruses will simply recirculate, and perhaps undergo mutations or changes that render vaccines useless, passing through the unprotected populations of the planet.
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