There are two possible outcomes: if the result confirms the hypothesis, then you've made a measurement. If the result is contrary to the hypothesis, then you've made a discovery.
I have steadily endeavored to keep my mind free so as to give up any hypothesis, however much beloved (and I cannot resist forming one on every subject), as soon as the facts are shown to be opposed to it.
The great tragedy of science - the slaying of a beautiful hypothesis by an ugly fact.
In order to shake a hypothesis, it is sometimes not necessary to do anything more than push it as far as it will go.
For every fact there is an infinity of hypotheses.
I cannot give any scientist of any age better advice than this: the intensity of a conviction that a hypothesis is true has no bearing over whether it is true or not.
Truth in science can be defined as the working hypothesis best suited to open the way to the next better one.
It is an hypothesis that the sun will rise tomorrow: and this means that we do not know whether it will rise.
[One's] inability to invalidate your hypothesis is not at all the same thing as proving it true.
If the facts are contrary to any predictions, then the hypothesis is wrong no matter how appealing.
Hypotheses non fingo. I frame no hypotheses.
I am not here concerned with intent, but with scientific standards, especially the ability to tell the difference between a fact, an opinion, a hypothesis, and a hole in the ground.
I would be lying, however, if I claimed that I could always formulate worthwhile hypotheses on the basis of my theoretical framework. Sometimes there were no reflexive processes to be found; sometimes I failed to find them; and, what was the most painful of all, sometimes I got them wrong. One way or another, I often invested without a worthwhile hypothesis and my activities were not very different from a random walk.
I feign no hypotheses.
A fact is a simple statement that everyone believes. It is innocent, unless found guilty. A hypothesis is a novel suggestion that no one wants to believe. It is guilty, until found effective.
The shrewd guess, the fertile hypothesis, the courageous leap to a tentative conclusion - these are the most valuable coins of the thinker at work. But in most schools guessing is heavily penalized and is associated somehow with laziness.
One must credit an hypothesis with all that has had to be discovered in order to demolish it.
It is a good morning exercise for a research scientist to discard a pet hypothesis every day before breakfast. It keeps him young.
The hypotheses we accept ought to explain phenomena which we have observed. But they ought to do more than this: our hypotheses ought to foretell phenomena which have not yet been observed.
I long ago suggested the hypothesis, that in the basin of the Thames there are indications of a meeting in the Pleistocene period of a northern and southern fauna.
I have not been able to discover the cause of those properties of gravity from phenomena, and I frame no hypotheses; for whatever is not deduced from the phenomena is to be called a hypothesis, and hypotheses, whether metaphysical or physical, whether of occult qualities or mechanical, have no place in experimental philosophy.
The word 'belief' is a difficult thing for me. I don't believe. I must have a reason for a certain hypothesis. Either I know a thing, and then I know it - I don't need to believe it.
The greatest problem for mathematicians now is probably the Riemann Hypothesis.
Even mistaken hypotheses and theories are of use in leading to discoveries. This remark is true in all the sciences. The alchemists founded chemistry by pursuing chimerical problems and theories which are false. In physical science, which is more advanced than biology, we might still cite men of science who make great discoveries by relying on false theories.
It is absolutely essential that one should be neutral and not fall in love with the hypothesis.
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