Humor is by far the most significant activity of the human brain.
Sometimes one creates a dynamic impression by saying something, and sometimes one creates as significant an impression by remaining silent.
Democrats and Republicans were essentially the same party with different faces and that was why, no matter how many promises each leader made, significant change rarely transpired.
It seems essential, in relationships and all tasks, that we concentrate only on what is most significant and important.
The best time to do something significant is between yesterday and tomorrow.
True power and true happiness are when you use your success to make others around you feel even more significant.
It is very difficult to explain this feeling to anyone who is entirely without it, especially as there is no anthropomorphic conception of God corresponding to it. The individual feels the nothingness of human desires and aims and the sublimity and marvelous order which reveal themselves both in Nature and in the world of though. He looks upon individual existence as a sort of prison and wants to experience the universe as a single significant whole.
A life is not important except in the impact it has on other lives.
Hitherto the principle of causality was universally accepted as an indispensable postulate of scientific research, but now we are told by some physicists that it must be thrown overboard. The fact that such an extraordinary opinion should be expressed in responsible scientific quarters is widely taken to be significant of the all-round unreliability of human knowledge. This indeed is a very serious situation.
People are stereotypes, they are caricaturized. It comes from both sides of the political aisle, it comes from the press. It's all about conflict, it's all about personality, and there are huge stakes in the policies that are being debated, and I think there's a hunger amongst a very significant, maybe even a critical mass of Americans, clustered on the left, right, and center, to have an adult conversation about how we're going to solve these problems ... but it's not for the fainthearted.
To study the meaning of man and of life — I am making significant progress here. I have faith in myself. Man is a mystery: if you spend your entire life trying to puzzle it out, then do not say that you have wasted your time. I occupy myself with this mystery, because I want to be a man.
The Central Intelligence Agency owns everyone of any significance in the major media.
Only rarely do we see beyond the needs of humanity, and he linked this blindness to our Christian and humanist infrastructure. It arose 2,000 years ago and was then benign, and we were no significant threat to Gaia. Now that we are over six billion hungry and greedy individuals, all aspiring to a first-world lifestyle, our urban way of life encroaches upon the domain of the living Earth.
One other fact is significant: the domestic feasts and sacrifices of single families, which in David's time must still have been general, gradually declined and lost their importance as social circles widened and life became more public.
Things that are very significant and important to you when constructing an identity when you're younger change.
Patrick White is a strongly individual, richly gifted, original and highly significant writer whose powers are remarkable and whose achievement is large. His art is dense, poetic, and image-ridden. It is always a substantial and genuine thing. At its finest it is one which goes beyond an art of mere appearances to one of mysterious actuality.
The roots of great innovation are never just in the technology itself. They are always in the wider historical context. They require new ways of seeing. As Einstein put it, 'The significant problems we face cannot be solved at the same level of thinking we were at when we created them.'
Daren Hardy's The Compound Effect is a culmination of success principles that is relevant to anyone who needs it! As a thought leader, he is making a significant contribution to our industry. A wonderful book!
Terrorism is a significant threat to peace and security, prosperity and people.
... while I bathed, while I tried but failed to sleep, I considered how I might become more like the women I respected and admired. Surrounded as I was by ambitious, accomplished women, I couldn't ignore the little voice in my head that said maybe I was supposed to shed halfway, and do something significant. Contribute something. Accomplish something. Choose. Be.
I believe the single most significant decision I can make on a day-to-day basis is my choice of attitude... When my attitudes are right theres no challenge too great for me.
In the state of Alabama we have a significant number of illegal aliens that are leaving our state as occurred in Arizona after they got tough on illegal aliens.
In the end, people don't view their life as merely the average of all its moments-which, after all, is mostly nothing much plus some sleep. For human beings, life is meaningful because it is a story. A story has a sense of a whole, and its arc is determined by the significant moments, the ones where something happens. Measurements of people's minute-by-minute levels of pleasure and pain miss this fundamental aspect of human existence. A seemingly happy life maybe empty. A seemingly difficult life may be devoted to a great cause. We have purposes larger than ourselves.
To allow public access to orbit, we would need breakthroughs that would lower the cost by a lot more than an order of magnitude and increase safety by a factor of 100 as compared to every launch system used since the first manned space flight. I think airborne launch will be a significant part of the safety solution.
Moreover, if one selects a problem, works on it in isolation for a few years and finally solves it, there is a danger, unless the problem is very famous, that it will no longer be regarded as all that significant.
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